Explore the routes to reach Greenwood, South Carolina
If you're coming from Greenville/Spartanburg, SC, hop onto I-85 and take exit 46B onto Hwy 291. Continue until it merges with Hwy 25 S.
Stay on Hwy 25 S for about 55 miles until you reach Greenwood.
From Columbia, SC or I-26, take exit 54 onto Hwy 72 W. Follow Hwy 72 W for around 35 miles until you arrive at Greenwood.
Are you travelling from Athens, GA? Head out on Hwy 72 E toward Greenwood for approximately 75 miles.
If you're journeying from Augusta, GA, take Hwy 25 N through North Augusta, SC, toward Greenwood. It's roughly 50 miles away.
